METABOLIC CHARACTERIZATION OF AGGRESSIVE BREAST CANCER CELLS EXHIBITING INVASIVE PHENOTYPE: IMPACT OF NON-CYTOTOXIC DOSES OF 2-DG ON DIMINISHING INVASIVENESS

Abstract Background Metabolic reprogramming is being recognized as a fundamental hallmark of cancer, and efforts to identify drugs that can target cancer metabolism are underway.In this study, we used human breast cancer (BC) cell lines and established their invading phenotype (INV) collected from transwell inserts to compare metabolome differences

Bio-leaching is a non-invasive, relatively affordable and environmentally friendly method through which toxic compounds are decomposed with the help of microorganisms and with the help of enzymatic reactions.This study was conducted in order to use biological leaching in order to rehabilitate soil contaminated and resistant to biological decomposit

BackgroundMicroRNAs (miRNAs) play critical roles in regulating virus infection and replication.However, the mechanism by which miRNA regulates Zika virus (ZIKV) replication remains elusive.We aim to explore how the differentially expressed miR-103a-3p regulates ZIKV replication and to clarify the underlying molecular mechanism.MethodsSmall RNA sequ

This paper proposes a functional safety and information Assessing protopectin transformation potential of plant tissue using a zoned criterion space security protection mechanism based on blockchain technology.The design of the basic level and integration level blockchain structure of CPS distributed architecture and related functional safety and i